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Acetyl-L-Carnitine 500 mg Bioavailability Study


Bioavailability Study

Acetyl-L-Carnitine is a modified amino acid that supports cellular energy production by assisting in the transport of fat into the mitochondria, where it is oxidized and converted into ATP.

Three healthy adult volunteers, 22 to 55 years old, participated in a clinical trial to study the bioavailability of Acetyl L-Carnitine 500 mg, a dietary supplement from NOW® (# 0076). Total serum carnitine was measured at baseline, and again at 1, 3, and 6 hours following oral administration of 2 capsules providing 1 gram (1,000 mg) of acetyl-L-carnitine.


Average serum carnitine peaked three hours after supplement administration, reaching 25% over the baseline level. Six hours post-supplementation, average carnitine concentration remained elevated 20% over the baseline level. This study confirms the exceptional bioavailability of NOW® Acetyl-L-Carnitine 500 mg Veg Caps from NOW®.

Average total serum carnitine level before, and 1, 3, and 6 hours following a single administration of two Acetyl-L-Carnitine 500 mg Veg Capsules (NOW®, Bloomingdale, Illinois; #0076) providing 1,000 mg of acetyl-L-carnitine in healthy adult volunteers.

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