SAMe 400 mg Tablets

  • Helps reduce pain associated with Osteoarthritis
  • Enteric Coated
  • Maximum Strength 400mg
  • Vegetarian / Vegan
SAMe (S-adenosylmethionine), a compound native to the body, is a critical component of many biochemical reactions, including those that affect brain biochemistry and joint health. SAMe is critical for the synthesis of neurotransmitters, is important for energy production in the brain, contributes to the maintenance of healthy cell membrane function, and influences cartilage metabolism. NOW® SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation during digestion. This 400mg dosage is our strongest offering, helping to reduce the number of pills needed per day and suitable for more severe health conditions.

NPN 80015259




More Information

Size Servings SKU UPC
30 Tablets 30 NOW80139 733739801395

Adult Dosage: Take 1 tablet, 3 times daily on an empty stomach. Use for a minimum of 2 weeks to see beneficial effects. Refrigerate after opening.

Each tablet contains:

S-Adenosylmethionine 400 mg
(from S-Adenosyl-L-Methionine Disulfate Tosylate)

Non-Medicinal Ingredients: Cellulose, Croscarmellose Sodium, Magnesium Stearate (vegetable source), Silica, Stearic Acid (vegetable source), Citric Acid, Ascorbic Acid, Tablet Coating, (methacrylic acid, hypromellose, calcium carbonate, hydroxypropyl cellulose, glycerin).

Do not use if you have been diagnosed with Bipolar Disorder or if you are pregnant or breastfeeding. Do not use this product within 2 weeks of discontinuing a Monoamine Oxidase Inhibitor (MAOI) drug. Consult a health care practitioner before use if you are taking any other medications. Flatulence, nausea, vomiting, diarrhea, constipation, dry mouth, mild insomnia, sweating, dizziness and nervousness may occur.

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