Ensure you are up-to-date on mammograms and gynaecological evaluations prior to use. Consult a health care practitioner prior to use if symptoms worsen, if you have human herpes virus, or if you are taking cyclosporine, estrogens, birth control medications, medroxyprogesterone, norethindrone, nitrates, potassium-increasing drugs, sildenafil, xylitol, aminophyllin, blood thinners, hormone replacement therapy (HRT) including thyroid HRT, or medication for cardiovascular diseases or erectile dysfunction. Consult a health care practitioner prior to use if you have a history of hormonal or gynaecological disease, including ovarian cancer, endometriosis, and/or uterine fibroids, if you have a liver disorder or develop liver-related symptoms (e.g. abdominal pain, jaundice, dark urine), if your cardiovascular condition worsens, if you have a renal/kidney disease, if you are following a low protein diet, or if you suffer from a cardiovascular disease and are attempting an increase in physical activity. Discontinue use and consult a health care practitioner if you experience breast pain, discomfort and/or tenderness, or if you experience a recurrence of menstruation and/or uterine spotting. Do not use if you currently have or previously had breast cancer and/or breast tumours, or if you have a predisposition to breast cancer, as indicated by an abnormal mammogram and/or biopsy, or a family member with breast cancer. Do not use if you have had a heart attack/myocardial infarction, or if you are allergic to cow milk products. Do not use if you have sickle cell anemia, hypertension, gout, decreased platelet count, elevated blood-urea nitrogen, serum creatine and creatinine, delayed menses, asthma, a hypersensitivity to L-Ornithine or ornithine supplements, are Ornithine Delta-Aminotransferase deficient, or are pregnant or breastfeeding. Some people may experience gastrointestinal discomfort (such as diarrhea).