Magnesium Citrate Softgels Pharmacokinetic (pK) Study
Magnesium Citrate Softgels provide magnesium in three forms (citrate, glycinate, and malate). Magnesium is a mineral involved in metabolism, muscle contraction, nerve impulse transmission, and bone mineralization. Three healthy adult volunteers 26 to 59 years old participated in a clinical trial to study the bioavailability of Magnesium Citrate Softgels, a dietary supplement from NOW® (item # 1290). Serum magnesium concentration was measured at baseline, and at 1, 4, and 24 hours following oral administration of three Magnesium Citrate Softgels, providing 400 mg elemental magnesium.
Average magnesium peaked 4 hours after supplementation, reaching 7% above the baseline level. Average magnesium returned to the near-baseline levels 24 hours post-supplementation, about 3% over the baseline level. The study confirms the bioavailability of NOW® Magnesium Citrate Softgels.