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Magnesium Citrate Softgels Pharmacokinetic (pK) Study


Bioavailability study

Magnesium Citrate Softgels provide magnesium in three forms (citrate, glycinate, and malate). Magnesium is a mineral involved in metabolism, muscle contraction, nerve impulse transmission, and bone mineralization.* Three healthy adult volunteers 26 to 59 years old participated in a clinical trial to study the bioavailability of Magnesium Citrate Softgels, a dietary supplement from NOW® (item # 1290). Serum magnesium concentration was measured at baseline, and at 1, 4, and 24 hours following oral administration of three Magnesium Citrate Softgels, providing 400 mg elemental magnesium.


Average magnesium peaked 4 hours after supplementation, reaching 7% above the baseline level. Average magnesium returned to the near-baseline levels 24 hours post-supplementation, about 3% over the baseline level. The study confirms the bioavailability of NOW® Magnesium Citrate Softgels.

*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.


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